Threshold #110 | How to boost your mitochondrial health to improve muscle strength 🧬

How you train your mitochondria can transform your performance.

In recent years, science has revealed just how critical these tiny powerhouses are for endurance and strength.

Optimizing mitochondrial health can unlock faster recovery, greater energy, and stronger muscles.

So, how can you supercharge your mitochondria to boost your muscle strength?

P.S. Did you read yesterday’s Clubhouse post? Read it here.

TL;DR

  • Boosts Endurance and Strength: This workout enhances mitochondrial efficiency, improving energy output and muscle performance during sustained efforts.

  • Increases Recovery: Alternating between high-intensity intervals and active recovery builds mitochondrial density, allowing for faster recovery and reduced fatigue.

  • Long-Term Performance Gains: By targeting energy systems and building aerobic capacity, this workout supports better endurance, strength, and overall physical performance.

As we age, our muscles naturally lose mass, strength, and functionality, which can lead to fatigue and weakness beginning as early as our 30s. Recent studies indicate that our mitochondria—the cellular powerhouses that generate 90% of our energy—play a crucial role in this decline, contributing to reduced muscle function as we age.

A new way to support and improve muscle health as we age, Mitopure® by Timeline is clinically shown to meaningfully boost our mitochondrial health to improve muscle strength and endurance, without any change in exercise required.

The Main Feature: How to Boost Your Mitochondrial Health to Improve Muscle Strength 🧬

Mitochondria are the unsung heroes of athletic performance. Known as the powerhouses of your cells, they’re responsible for producing the energy your muscles need to perform, adapt, and grow. But mitochondrial health isn’t just about energy—it impacts endurance, recovery, and even resilience against fatigue. Enhancing mitochondrial function requires targeted training, optimized nutrition, and intentional recovery. Here’s a deep dive into how to supercharge your mitochondria and, in turn, your muscle strength.

Leg one: Training to Build Resilient Mitochondria

Mitochondria thrive on movement—regular exercise is their ultimate catalyst for growth and efficiency. Through mitochondrial biogenesis, your cells adapt to training by increasing the number and functionality of mitochondria. A balanced approach that includes aerobic, anaerobic, and resistance training is key to unlocking these adaptations.

Have a great week of training everyone and make sure to focus on your mental strenght and leg day.

Zone 2 Training: The Foundation of Mitochondrial Health

Zone 2 training is a game-changer for mitochondrial efficiency. Exercising at 60–70% of your max heart rate engages fat metabolism, which requires mitochondrial involvement. Over time, this type of low-intensity aerobic work increases the size and number of mitochondria, building a solid energy base.

How to Incorporate Zone 2:

• Aim for 2–4 sessions per week, each lasting 30–60 minutes.

• Activities like steady-state running, cycling, or rowing work well.

• Keep your pace conversational, but monitor with a heart rate monitor for accuracy.

HIIT: For Maximum Mitochondrial Stress and Recovery

High-intensity interval training (HIIT) complements Zone 2 by pushing your mitochondria to their limits and forcing recovery adaptations. The intensity teaches your cells to manage oxidative stress and replenish energy stores efficiently.

Example HIIT Protocol:

• Warm up for 5–10 minutes at a moderate pace.

• Perform 6–8 rounds of 30 seconds at near-max effort, followed by 1-minute active recovery.

• Cool down with easy movement for 5–10 minutes.

Strength Training: Mitochondrial Power in Action

Strength training doesn’t just build muscle—it challenges mitochondria in Type II fibers, which are typically less reliant on oxidative energy. Compound movements like squats, deadlifts, and overhead presses improve mitochondrial adaptability and overall muscular function.

T-1: Mental Preparation

Your mitochondria are the engines powering every move you make. By optimizing their health, you’re unlocking greater endurance, faster recovery, and enhanced strength. Think of it as upgrading your internal hardware—stronger mitochondria mean more energy, better focus, and resilience. Prioritize this invisible powerhouse to elevate not just performance, but overall vitality.

Threshold Performance Club

Leg 2: Nutrition: Fueling Your Cellular Powerhouses

Your mitochondria rely on a steady supply of nutrients to function optimally. The right macronutrients and micronutrients support energy production, repair oxidative damage, and enhance mitochondrial efficiency.

Macronutrient Balance for Mitochondrial Health

Healthy Fats: Mitochondria thrive on fats during aerobic activity. Incorporate avocados, nuts, seeds, and fatty fish.

Carbohydrates: Essential for high-intensity efforts, carbs replenish glycogen stores and fuel mitochondria during intense exercise. Stick to whole grains, fruits, and root vegetables.

Proteins: Post-workout recovery is critical for mitochondrial repair. Lean meats, eggs, and plant-based proteins like quinoa or tofu are ideal options.

Key Micronutrients to Include

Coenzyme Q10 (CoQ10): Supports ATP production and reduces oxidative stress. Found in organ meats, fish, and peanuts.

Magnesium: Vital for enzymatic reactions within the mitochondria. Found in dark leafy greens, nuts, and whole grains.

Omega-3 Fatty Acids: Improve mitochondrial membrane health, found in salmon, walnuts, and chia seeds.

B Vitamins: Act as cofactors in energy metabolism. Foods like eggs, legumes, and leafy greens are rich sources.

Intermittent Fasting for Cellular Cleansing

Intermittent fasting triggers autophagy, the body’s process of clearing out damaged mitochondria and replacing them with newer, healthier versions. Start with a 12:12 fasting window and gradually progress to 16:8 as tolerated.

T-2: Gear of the week: Shop supplements to enhance performance

This Holiday Season, Give Yourself the Gift of Nike Air Max.

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Find the perfect pair that matches your lifestyle and get ready to make a statement with every step. Treat yourself to a fresh pair from the collection this holiday season—you deserve it.

☕️ DIRTEA Coffee is packed with a high dose of Lion’s Mane, Chaga, and Tremella, together with adaptogens Ashwagandha and Maca, scientifically proven to enhance your focus.Buy now.

🍄 DIRTEA Cordyceps may improve physical performance as well as increase energy levels. It provides vitality throughout the day and boosts endurance during a workout. Perfect for VO2 max. Buy now.

Buy mushroom supplements today at DIRTEA. Enhance training and maximise performance.

Leg 3: Recovery: The Hidden Engine of Mitochondrial Health

Mitochondrial health thrives on recovery. During rest, your cells repair and grow stronger, adapting to the stresses you’ve placed on them. Optimizing recovery ensures your mitochondria can keep up with your training demands.

Prioritize Deep, Restorative Sleep

Sleep is the cornerstone of recovery. During deep sleep stages, your body produces hormones like melatonin, which acts as an antioxidant for mitochondrial repair. Aim for 7–9 hours of high-quality sleep each night and maintain a consistent sleep schedule.

Cold Exposure for Mitochondrial Adaptation

Cold exposure activates brown adipose tissue, which is rich in mitochondria. This process enhances mitochondrial activity and resilience. Start with cold showers or ice baths for 30–60 seconds, gradually increasing duration over time.

Stress Management for Mitochondrial Efficiency

Chronic stress floods your body with cortisol, which can impair mitochondrial function. Engage in activities like yoga, meditation, or nature walks to keep stress in check.

Why the Nike Invincible 3 is Ideal for Recovery Runs

Recovery runs, especially in Zone 2, are essential for mitochondrial health. The Nike Invincible 3 provides unmatched cushioning with React foam, reducing muscle fatigue and encouraging active recovery. Its wide platform minimizes the risk of injury, allowing you to focus on consistent, mitochondria-friendly training.

Unlocking Your Cellular Potential

Optimising mitochondrial health is a game-changer for muscle strength and endurance. Through structured training like Zone 2 and HIIT, nutrient-dense eating with targeted supplementation, and intentional recovery, you can unlock the full potential of these cellular powerhouses.

By taking care of your mitochondria, you’re not only boosting your athletic performance but also investing in your long-term health and vitality. Start small, stay consistent, and watch as your body transforms from the inside out.

So that’s how optimising mitochondrial health can enhance muscle strength.

Aid station: Learn as you recover

Learn from other sources:

🧠 Thrive25 is a 5 minute newsletter dedicated to health & longevity. Find out how to live smarter, better and longer.

🧠 Discover the latest scientific health research with Huberman Lab.

🎖️ Level up your discipline listening to retired Navy SEAL Jocko Willink sharing advice.

Coaches Corner

Strong mitochondria are the foundation of athletic success. Better mitochondrial health means you recover faster, perform stronger, and sustain energy longer. Training smarter with Zone 2 runs and focused recovery isn’t just about workouts—it’s about building resilience at the cellular level to maximize your potential.

Threshold Performance Coach

TRAINING PLANS TO HELP YOU PERFORM

🏃🏋️‍♀️ Transform your body with The HYBRID Programme: A tailored 6 or 8 Week Running, Lifting & Nutrition Plan. Every single daily workout detailed in full.

🏃 Get The RUNNING Programme: Become a Faster Runner in 6-Weeks. 4 detailed sessions a week including base run, sprint, tempo & pyramid runs.

🥦 Get the Nutrition Guide for Athletes: The Diet & Nutrition Guide for Training. Everything you need for carb-loading and fuelling for your training sessions. Includes meal planner & detailed recipes.

Workout of the Week: 60-Minute Mitochondria Builder

This workout is designed to boost mitochondrial efficiency and improve endurance, helping your muscles sustain high energy output over longer efforts. By combining steady aerobic work with intensity bursts, you’ll enhance your energy systems and build lasting strength.

Total Duration: 60 minutes

Workout Structure:

Minutes 0-15: Warm-Up

• Start in Zone 2 (60-70% of Max HR).

• Gradually increase your pace every 5 minutes.

• Include 3 x 30-second bursts at high intensity during the last 5 minutes.

Focus: Gently activate your cardiovascular system and prepare your muscles for exertion.

Minutes 15-30: Aerobic Efficiency Intervals

• 3 x 5-minute steady intervals at Zone 2 (70% of Max HR).

• Between intervals, recover for 1 minute at a light jog or walk.

Focus: Strengthen mitochondria and improve fat-burning capacity.

Minutes 30-60: VO2 Max Ladder Intervals

• 5-minute sets alternating between:

• 1 minute at 90% effort (near VO2 max)

• 2 minutes at Zone 2 (active recovery)

• Repeat until the 5 minutes are complete, then take 2 minutes walking rest.

• Complete 4 sets.

Focus: Enhance mitochondrial density and your muscles’ ability to handle high-intensity efforts.

Additional Tips:

1. Hydration and Fueling:

• Stay hydrated, and for workouts exceeding an hour, consider taking an electrolyte drink or small carbs like gels.

2. Pacing and Form:

• During intervals, focus on controlled breathing to stay efficient and reduce fatigue.

3. Customization:

• Adjust the intensity to match your fitness level while staying consistent with effort zones.

By consistently integrating this session into your routine, you’ll stimulate mitochondrial growth and efficiency, resulting in better endurance and muscle strength over time.

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Have a great week,

Robert

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I spend a lot of time working in different sectors from marketing to e-commerce to fintech. The tips I’ve learned from these other interests have massively helped me become a better human.

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